Task Group 113
Reference Organ and Effective Dose Coefficients for Common Diagnostic X-ray Imaging Examinations

A Task Group under Committee 2 and Committee 3

 

The primary dosimetric data on exposures in X-ray imaging procedures are measurements of entrance air kerma (for radiography), air kerma-area products (for diagnostic fluoroscopy), and CTDIvol and DLP (for computed tomography, CT). Such dose metrics are used to set Diagnostic Reference Levels that allow comparisons of doses received from the same procedure in different hospitals and help ensure that exposures are the minimum required to produce appropriate quality of images. However, effective dose is also used extensively in diagnostic x-ray imaging to provide a detriment-related dose quantity to inform clinical judgements, including the comparison of different x-ray procedures, and comparisons of imaging practice across different hospitals and medical facilities. For many years, the ICRP has produced, through its joint C2/C3 Task Group 36, reference dose coefficients for common diagnostic nuclear medicine procedures. However, ICRP has not provided reference dose coefficients for X-ray imaging procedures and consequently different methodologies are used to convert measurements to estimates of effective dose or some surrogate of effective dose. These calculations necessarily rely on disparate published data based on the use of older stylized hermaphrodite phantoms that are not in alignment with the most recent ICRP reference phantoms. In addition, different computational methods for radiation transport have been used to report organ doses from which the effective dose is computed. Those responsible for such calculations and their interpretation would welcome the availability of ICRP reference organ and effective dose coefficients.

Effective dose is also used to provide a common basis for assessing the medical component of radiation exposure to populations of individual countries or world-wide. Currently, the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) is assembling data on medical exposures in Member States. Meanwhile, the US National Council on Radiation Protection and Measurement (NCRP) is updating its Report 160, which is on medical exposures to the US population. The availability of ICRP reference dose coefficient for diagnostic X-ray procedures as well as nuclear medicine procedures would help standardize the reporting of doses for these applications.

The proposed Task Group has three major tasks. Task A is to define reference imaging exams for the ICRP reference individuals, male and female newborn, 1-year-old, 5-year-old, 10-year-old, 15-year-old, and adult, for radiography (both DR and CR), diagnostic fluoroscopy, interventional fluoroscopy, and computed tomography. These reference imaging exams would not be expected to cover the full range of clinical practice and would be limited to x-ray technique factors that would be clinically consistent with imaging the body morphometry of the reference individuals. For example, a reference abdominal CT exam would not encompass technique factors that would be needed for optimal imaging of a very short, and very obese adult male (e.g., kVp, mA, etc.) since the reference adult male is not short nor obese. These reference imaging exams would be developed within the Task Group with an eye toward consistency with national and international optimized and recommended imaging protocols for each modality. Reference imaging exams for interventional fluoroscopy would most likely be limited to common procedures that are anatomy focused (e.g., cardiac interventional procedures), fully acknowledging that each patient intervention can be highly variable regarding imaged anatomy, combination of fluoroscopy, cine, and radiographic spot imaging, and total procedure time. These reference imaging exams would be fully analogous to the reference biokinetic models established by Task Group 36 on diagnostic nuclear medicine organ and effective dose coefficients, recognizing that each individual patient may metabolize the radiopharmaceutical in a manner that may substantially differ from the reference model.

Task B is to perform Monte Carlo radiation transport simulations for the reference imaging exams and to report organ absorbed dose and effective dose coefficients for each of the reference computational phantoms and for each of the relevant reference imaging exam. The scope of this work would be limited to the use of the reference computational phantoms of the ICRP, male and female newborn, 1-year-old, 5-year-old, 10-year-old, 15-year-old, and adult. In addition, the Task Group would employ the recently developed ICRP pregnant female phantom series to include all, or a subset of, the 8-member phantom series: 8-week, 10-week, 15-week, 20-week, 25-week, 30-week, 35-week, and 38-week (post-conception) phantoms.

There are increasing demands by medical professions and relevant regulatory agencies to document patient-specific exposures to diagnostic medical imaging procedures. As such, various software tools have been developed which are built upon extensive libraries of computational phantoms covering a wide array of body morphometries, with algorithms for matching patient to phantom. Other methods, such as in CT, can even use the patient’s own CT image as the basis for a patient-specific phantom for dose assessment. These developments are beyond the mandate of the proposed task group. However, a Task C is proposed to compute and compare organ doses in the 10th and 90th body height / weight percentiles for patient populations with the values obtained for the reference individuals under Task B. When patient-specific organ doses (single gender) are weighted by radiation and tissue weighting factors, the result is not the effective dose (which is unfortunately widely reported), and this can be clarified in the report.

Nina Petoussi-Henss (Co-Chair), Helmholtz Zentrum München, Germany
David Sutton (Co-Chair), NHS Tayside / University of Dundee, UK
Wesley E. Bolch (Member), University of Florida, USA
Jan T.M. Jansen (Member), Public Health England, UK
Chan Hyeong Kim (Corresponding Member), Hanyang University, Korea
Yusuke Koba (Corresponding Member), National Institute of Radiological Sciences, Japan
Choonsik Lee (Member), National Cancer Institute, USA
Pasquale Alessandro Lombardo (Corresponding Member), SCK.CEN, Belgium
Donald L. Miller (Corresponding Member), Center for Devices and Radiological Health Food and Drug Administration, USA
Helmut Schlattl (Member), Helmholtz Zentrum München , Germany
Ioannis Sechopoulos (Member), Radboud University Medical Center & Dutch Expert Centre for Screening (LRCB), Netherlands
Sabastian Trinkl (Corresponding Member), Germany
Maria Zankl (Corresponding Member), Helmholtz Zentrum München, Germany